This is the first course in a 2-semester investigation into the engineering of medical imaging modalities. These courses will provide the student with a functional understanding of some of the most common applications of engineering in medical imaging. This will include discussions of the underlying physics, device operation, image formation, and clinical applications of medical images including in-depth discussions on magnetic resonance imaging (MRI), ultrasound (US), and optical imaging. We will also examine the important topics of image resolution, signal-to-noise, radiation dose, image analysis, clinical decision-making in relation to diagnostic imaging, and emerging techniques in machine learning. All of these modalities involve some interaction of matter with waves (electromagnetic waves, sound waves, etc.). To appropriately understand these modalities requires a solid grasp of fundamental concepts taught within undergraduate level physics, mathematics, and engineering courses. This is an upper-level undergraduate/graduate course specifically targeted toward students with interest in careers in biomedical engineering, clinical technology, and medicine. Thus, a large portion of lecture will be dedicated to both theoretical development and applications in research and medicine. Of course, the ultimate goal of this course (and hopefully every course you take in higher education) is to develop the student to be a critical thinker!